Mahaira-Odoni taught political theory and international law and has published articles and critical reviews for Telos, particularly on the philosophy of Sartre. As a vocalist with the New England Conservatory, Odoni produced a CD, Mistral, following other recordings. She edited and translated into Greek Monteagle Stearns' Entangled Allies: US Policy in Greece, Turkey, and Cyprus, as well as G.T. Allison and K. Nicolaidis' (editors), The Greek Paradox: Promise vs. Performance. Her research focuses on Venetian history in thirteenth-century Greece and on the link between history and literature (CES Working Papers Series publications). Mahaira-Odoni co-chairs the Greek Study Group.